Understanding Human Gamma Delta T Cell-HIV Interactions: Insights from the BLT Humanized Mouse Model

EasyChair Preprint 12351

Abstract

The BLT (bone marrow, liver, thymus) humanized mouse model has emerged as a valuable and indispensable tool for exploring the interactions between human gamma delta (γδ) T cells and Human Immunodeficiency Virus (HIV) within an in vivo environment. This research paper provides a comprehensive review of the current state of knowledge concerning the BLT humanized mouse model, with a specific emphasis on its efficacy in deciphering the intricate dynamics between γδ T cells and HIV. The paper delves into the construction of the BLT model, outlines its advantages and limitations, and highlights the pivotal insights it has contributed to understanding the interplay between γδ T cells and HIV pathogenesis.

Keyphrases: BLT Humanized Mouse Model, Gamma Delta T Cell, HIV Interactions

@booklet{EasyChair:12351,
  author    = {Saba Shehzadi},
  title     = {Understanding Human Gamma Delta T Cell-HIV Interactions: Insights from the BLT Humanized Mouse Model},
  howpublished = {EasyChair Preprint 12351},
  year      = {EasyChair, 2024}}